Fragment‐based drug discovery—the importance of high‐quality molecule libraries

Fragment‐based drug discovery (FBDD) is now established as a complementary approach to high‐throughput screening (HTS). Contrary to HTS, where large libraries of drug‐like molecules are screened, FBDD screens involve smaller and less complex molecules which, despite a low affinity to protein targets...

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Detalles Bibliográficos
Autores principales: Bon, Marta, Bilsland, Alan, Bower, Justin, McAulay, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627785/
https://www.ncbi.nlm.nih.gov/pubmed/35749608
http://dx.doi.org/10.1002/1878-0261.13277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627785/
https://www.ncbi.nlm.nih.gov/pubmed/35749608
http://dx.doi.org/10.1002/1878-0261.13277

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