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Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR‐based screens
The concepts of synthetic lethality and viability have emerged as powerful approaches to identify vulnerabilities and resistances within the DNA damage response for the treatment of cancer. Historically, interactions between two genes have had a longstanding presence in genetics and have been identi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627789/ https://www.ncbi.nlm.nih.gov/pubmed/35708734 http://dx.doi.org/10.1002/1878-0261.13272 |