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Circulating Furin-Cleaved Proprotein Convertase Subtilisin/Kexin Type 9 Concentration Predicts Future Coronary Events in Japanese Subjects

BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) circulates as mature and furin-cleaved forms, which differ in their properties to degrade low-density lipoprotein (LDL) receptors. OBJECTIVES: In this study, we sought to investigate whether PCSK9 subtypes associate with atherosclerot...

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Detalles Bibliográficos
Autores principales: Kataoka, Yu, Harada-Shiba, Mariko, Hori, Mika, Watanabe, Makoto, Kokubo, Yoshihiro, Noguchi, Teruo, Yasuda, Satoshi, Miyamoto, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627806/
https://www.ncbi.nlm.nih.gov/pubmed/36341208
http://dx.doi.org/10.1016/j.jacasi.2021.09.003