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Investigation of the causal relationship between ALS and autoimmune disorders: a Mendelian randomization study

BACKGROUND: Epidemiological studies have reported an association between amyotrophic lateral sclerosis (ALS) and different autoimmune disorders. This study aims to explore the causal relationship between autoimmune disorders and ALS using Mendelian randomization (MR). METHODS: To test the geneticall...

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Detalles Bibliográficos
Autores principales: Alipour, Paria, Senkevich, Konstantin, Ross, Jay P., Spiegelman, Dan, Manousaki, Despoina, Dion, Patrick A., Rouleau, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628014/
https://www.ncbi.nlm.nih.gov/pubmed/36320012
http://dx.doi.org/10.1186/s12916-022-02578-9