High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration

BACKGROUND: Relationship between cancer cell glycolysis and the landscape of tumor immune microenvironment in human cancers was investigated. METHODS: Forty-one fresh lung adenocarcinoma (ADC) tissues were analyzed using flow cytometry for comprehensive immunoprofiling. Formalin-fixed tissues were i...

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Detalles Bibliográficos
Autores principales: Kim, Sehui, Koh, Jaemoon, Song, Seung Geun, Yim, Jeemin, Kim, Miso, Keam, Bhumsuk, Kim, Young Tae, Kim, Jihun, Chung, Doo Hyun, Jeon, Yoon Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628070/
https://www.ncbi.nlm.nih.gov/pubmed/36320008
http://dx.doi.org/10.1186/s12885-022-10239-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628070/
https://www.ncbi.nlm.nih.gov/pubmed/36320008
http://dx.doi.org/10.1186/s12885-022-10239-6

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