Alterations of DNA methylation and expression of genes related to thyroid hormone metabolism in colon epithelium of obese patients

BACKGROUND: Colorectal cancer is common among obese individuals. The purpose of the current study was to determine changes in DNA methylation status and mRNA expression of thyroid hormone receptor beta (THRB), as a tumor suppressor, and thyroid hormone inactivating enzyme, type 3 deiodinase (DIO3) g...

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Detalles Bibliográficos
Autores principales: Shimi, Ghazaleh, Pourvali, Katayoun, Ghorbani, Arman, Nooshin, Sajad, Zare Karizi, Shohreh, Iranirad, Reza, Zand, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628115/
https://www.ncbi.nlm.nih.gov/pubmed/36320063
http://dx.doi.org/10.1186/s12920-022-01387-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628115/
https://www.ncbi.nlm.nih.gov/pubmed/36320063
http://dx.doi.org/10.1186/s12920-022-01387-6

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