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Alterations of DNA methylation and expression of genes related to thyroid hormone metabolism in colon epithelium of obese patients
BACKGROUND: Colorectal cancer is common among obese individuals. The purpose of the current study was to determine changes in DNA methylation status and mRNA expression of thyroid hormone receptor beta (THRB), as a tumor suppressor, and thyroid hormone inactivating enzyme, type 3 deiodinase (DIO3) g...
Autores principales: | Shimi, Ghazaleh, Pourvali, Katayoun, Ghorbani, Arman, Nooshin, Sajad, Zare Karizi, Shohreh, Iranirad, Reza, Zand, Hamid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628115/ https://www.ncbi.nlm.nih.gov/pubmed/36320063 http://dx.doi.org/10.1186/s12920-022-01387-6 |
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