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Intracellular antibody targeting HBx suppresses invasion and metastasis in hepatitis B virus‐related hepatocarcinogenesis via protein phosphatase 2A‐B56γ‐mediated dephosphorylation of protein kinase B

OBJECTIVES: Hepatitis B virus X (HBx) is closely associated with HBV‐related hepatocarcinogenesis via the inactivation of tumour suppressors. Protein phosphatase 2A (PP2A) regulatory subunit B56 gamma (B56γ), as a tumour suppressor, plays a critical role in regulating cellular phosphorylation signal...

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Detalles Bibliográficos
Autores principales: Che, Lin, Du, Ze‐Bang, Wang, Wei‐Hua, Wu, Jia‐Shen, Han, Tun, Chen, Yuan‐Yuan, Han, Pei‐Yu, Lei, Zhao, Chen, Xiao‐Xuan, He, Yun, Xu, Ling, Lin, Xu, Lin, Zhong‐Ning, Lin, Yu‐Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628248/
https://www.ncbi.nlm.nih.gov/pubmed/35811356
http://dx.doi.org/10.1111/cpr.13304