RF27 | LBSUN342 Ar-targeted Linked-read Sequencing Reveals Complex Ar Structural Variants In Castration Resistant Prostate Cancer Models

Androgen deprivation therapies are employed for the treatment of advanced prostate cancer to suppress the transcriptional activity of the androgen receptor (AR). However, over the course of therapy, AR transcriptional activity re-emerges, and the disease progresses to castration resistant prostate c...

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Detalles Bibliográficos
Autores principales: Zivanovic, Andrej, Munro, Sarah A, Miller, Jeffrey T, Li, Yingming, Passow, Courtney N, Dehm, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628272/
http://dx.doi.org/10.1210/jendso/bvac150.1864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628272/
http://dx.doi.org/10.1210/jendso/bvac150.1864

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