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From oncoproteins to spike proteins: the evaluation of intramolecular stability using hydropathic force field

Evaluation of the intramolecular stability of proteins plays a key role in the comprehension of their biological behavior and mechanism of action. Small structural alterations such as mutations induced by single nucleotide polymorphism can impact biological activity and pharmacological modulation. C...

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Detalles Bibliográficos
Autores principales: Agosta, Federica, Kellogg, Glen E., Cozzini, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628575/
https://www.ncbi.nlm.nih.gov/pubmed/36315295
http://dx.doi.org/10.1007/s10822-022-00477-y