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A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge

Orthopoxviruses such as variola and monkeypox viruses continue to threaten the human population. Monkeypox virus is endemic in central and western Africa and outbreaks have reached as far as the U.S. Although variola virus, the etiologic agent of smallpox, has been eradicated by a successful vaccina...

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Detalles Bibliográficos
Autores principales: Parker, Scott, D'Angelo, June, Buller, R. Mark, Smee, Donald F., Lantto, Johan, Nielsen, Henriette, Jensen, Allan, Prichard, Mark, George, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628779/
https://www.ncbi.nlm.nih.gov/pubmed/34530009
http://dx.doi.org/10.1016/j.antiviral.2021.105179