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Heterogeneity in the A33 protein impacts the cross-protective efficacy of a candidate smallpox DNA vaccine

We previously developed a gene-based vaccine, termed 4pox, which targets four orthopoxvirus proteins (A33, L1, B5, and A27). Because any subunit orthopoxvirus vaccine must protect against multiple species of orthopoxviruses, we are interested in understanding the cross-protective potential of our 4p...

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Detalles Bibliográficos
Autores principales: Golden, Joseph W., Hooper, Jay W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628866/
https://www.ncbi.nlm.nih.gov/pubmed/18482742
http://dx.doi.org/10.1016/j.virol.2008.04.003