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Isolation and Characterization of Engineered Nucleoside Deoxyribosyltransferase with Enhanced Activity Toward 2’-Fluoro-2’-Deoxynucleoside

Nucleoside deoxyribosyltransferase (NDT) is an enzyme that replaces the purine or pyrimidine base of 2′-deoxyribonucleoside. This enzyme is generally used in the nucleotide salvage pathway in vivo and synthesizes many nucleoside analogs in vitro for various biotechnological purposes. Since NDT is kn...

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Detalles Bibliográficos
Autores principales: Yoo, Yeon-Jin, Choi, Kang-Hyun, Kim, Byoung-Kyun, Choi, Si-Sun, Kim, Eung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628941/
https://www.ncbi.nlm.nih.gov/pubmed/35791073
http://dx.doi.org/10.4014/jmb.2204.04041