Cargando…
Isolation and Characterization of Engineered Nucleoside Deoxyribosyltransferase with Enhanced Activity Toward 2’-Fluoro-2’-Deoxynucleoside
Nucleoside deoxyribosyltransferase (NDT) is an enzyme that replaces the purine or pyrimidine base of 2′-deoxyribonucleoside. This enzyme is generally used in the nucleotide salvage pathway in vivo and synthesizes many nucleoside analogs in vitro for various biotechnological purposes. Since NDT is kn...
Autores principales: | Yoo, Yeon-Jin, Choi, Kang-Hyun, Kim, Byoung-Kyun, Choi, Si-Sun, Kim, Eung-Soo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Microbiology and Biotechnology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628941/ https://www.ncbi.nlm.nih.gov/pubmed/35791073 http://dx.doi.org/10.4014/jmb.2204.04041 |
Ejemplares similares
-
Ethenoguanines Undergo Glycosylation by Nucleoside 2′-Deoxyribosyltransferases at Non-Natural Sites
por: Ye, Wenjie, et al.
Publicado: (2014) -
Nucleoside 2'-Deoxyribosyltransferase from Psychrophilic Bacterium Bacillus psychrosaccharolyticus — Preparation of an Immobilized Biocatalyst for the Enzymatic Synthesis of Therapeutic Nucleosides
por: Fresco-Taboada, Alba, et al.
Publicado: (2014) -
Genome of the Psychrophilic Bacterium Bacillus psychrosaccharolyticus, a Potential Source of 2′-Deoxyribosyltransferase for Industrial Nucleoside Synthesis
por: Fresco-Taboada, Alba, et al.
Publicado: (2013) -
Rational Design of a Thermostable 2′-Deoxyribosyltransferase for Nelarabine Production by Prediction of Disulfide Bond Engineering Sites
por: Cruz, Guillermo, et al.
Publicado: (2022) -
Quantitation of cellular deoxynucleoside triphosphates
por: Ferraro, Paola, et al.
Publicado: (2010)