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Deoxypodophyllotoxin Induces ROS-Mediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma

Deoxypodophyllotoxin (DPT), a naturally occurring flavonolignan, possesses several pharmacological properties, including anticancer property. However, the mechanisms underlying DPT mode of action in oral squamous cell carcinoma (OSCC) remain unknown. This study aimed to investigate the anticancer ef...

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Detalles Bibliográficos
Autores principales: Seo, Ji-Hye, Yoon, Goo, Park, Seryoung, Shim, Jung-Hyun, Chae, Jung-Il, Jeon, Young-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628964/
https://www.ncbi.nlm.nih.gov/pubmed/36039387
http://dx.doi.org/10.4014/jmb.2207.07012