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Formal nucleophilic pyrrolylmethylation via palladium-based auto-tandem catalysis: switchable regiodivergent synthesis and remote chirality transfer

Although nucleophilic benzylation-type reaction to introduce various aromatic systems into molecules has been widely explored, the related pyrrolylmethylation version remains to be disclosed. Reported herein is a palladium-catalysed multiple auto-tandem reaction between N-Ts propargylamines, allyl c...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Li, Yu-Fan, Tan, Shun-Zhong, Ouyang, Qin, Chen, Zhi-Chao, Du, Wei, Chen, Ying-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628985/
https://www.ncbi.nlm.nih.gov/pubmed/36349271
http://dx.doi.org/10.1039/d2sc05210e