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Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters

Nickel-catalyzed asymmetric α-heteroarylation of ketones with fluorinated heteroarenes is reported via C–F bond activation. A series of ketones and 2-fluoropyridine derivatives with different functional groups proceed well to provide the corresponding products containing all-carbon quaternary stereo...

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Detalles Bibliográficos
Autores principales: Gu, Xiaodong, Liu, Kexin, Yang, Limin, Xie, Chengyi, Li, Mingliang, Wang, Jun (Joelle)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629005/
https://www.ncbi.nlm.nih.gov/pubmed/36382277
http://dx.doi.org/10.1039/d2sc03409c