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SS31 Ameliorates Podocyte Injury via Inhibiting OMA1-Mediated Hydrolysis of OPA1 in Diabetic Kidney Disease

Diabetic kidney disease (DKD) is currently one of the leading causes of end-stage renal disease (ESRD). Mitochondrial dysfunction in podocyte is involve in DKD development. However, whether early mitochondrial stabilization delays or reverses DKD progression has not been elucidated. SS31 is a novel...

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Detalles Bibliográficos
Autores principales: Yang, Qianqian, Xie, Wenjia, Wang, Xiao, Luo, Jing, Zhou, Yang, Cao, Hongdi, Sun, Qi, Jiang, Lei, Yang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629008/
https://www.ncbi.nlm.nih.gov/pubmed/36338294
http://dx.doi.org/10.3389/fphar.2021.707006