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Norbornene-tetrazine ligation chemistry for controlling RNA-guided CRISPR systems

In the present study, norbornene-tetrazine ligation chemistry is harnessed for developing clickable RNA switches in biological contexts. This RNA control strategy is explored with a variety of applications. We further demonstrate the application of RNA-based norbornene-tetrazine ligation chemistry f...

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Detalles Bibliográficos
Autores principales: Qi, Qianqian, Zhang, Yutong, Xiong, Wei, Liu, Xingyu, Cui, Shuangyu, Ye, Xiaofang, Zhang, Kaisong, Tian, Tian, Xiang Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629044/
https://www.ncbi.nlm.nih.gov/pubmed/36382274
http://dx.doi.org/10.1039/d2sc02635j