Phosphatidic acid suppresses autophagy through competitive inhibition by binding GAPC (glyceraldehyde-3-phosphate dehydrogenase) and PGK (phosphoglycerate kinase) proteins

Macroautophagy/autophagy is a finely-regulated process in which cytoplasm encapsulated within transient organelles termed autophagosomes is delivered to lysosomes or vacuoles for degradation. Phospholipids, particularly phosphatidic acid (PA) that functions as a second messenger, play crucial and di...

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Detalles Bibliográficos
Autores principales: Guan, Bin, Jiang, Yu-Tong, Lin, De-Li, Lin, Wen-Hui, Xue, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629070/
https://www.ncbi.nlm.nih.gov/pubmed/35289711
http://dx.doi.org/10.1080/15548627.2022.2046449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629070/
https://www.ncbi.nlm.nih.gov/pubmed/35289711
http://dx.doi.org/10.1080/15548627.2022.2046449

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