PA-X protein of H1N1 subtype influenza virus disables the nasal mucosal dendritic cells for strengthening virulence

PA-X protein arises from a ribosomal frameshift in the PA of influenza A virus (IAV). However, the immune regulatory effect of the PA-X protein of H1N1 viruses on the nasal mucosal system remains unclear. Here, a PA-X deficient H1N1 rPR8 viral strain (rPR8-△PAX) was generated and its pathogenicity w...

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Detalles Bibliográficos
Autores principales: Qin, Tao, Chen, Yulian, Huangfu, Dandan, Yin, Yinyan, Miao, Xinyu, Yin, Yuncong, Chen, Sujuan, Peng, Daxin, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629126/
https://www.ncbi.nlm.nih.gov/pubmed/36271710
http://dx.doi.org/10.1080/21505594.2022.2139474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629126/
https://www.ncbi.nlm.nih.gov/pubmed/36271710
http://dx.doi.org/10.1080/21505594.2022.2139474

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