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ODP207 Histone methylase MLL attenuates insulin secretion by reducing glucose sensitivity in mouse pancreas

BACKGROUND: Myeloid / Lymphoid or Mixed-lineage leukemia gene (MLL) is translocated to chromosome 11 long arm q23 region (11q23) and the MLL fusion gene expressed as a result of translocation reconstruction plays an important role in MLL-related leukemia development. It has also been reported that M...

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Detalles Bibliográficos
Autores principales: Yoshino, Satoshi, Horiguchi, Emi Ishida Kazuhiko, Matsumoto, Shunichi, Yamada, Eijiro, Yamada, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629286/
http://dx.doi.org/10.1210/jendso/bvac150.659