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UBE2T promotes breast cancer tumor growth by suppressing DNA replication stress

Breast cancer is a leading cause of cancer-related deaths among women, and current therapies benefit only a subset of these patients. Here, we show that ubiquitin-conjugating enzyme E2T (UBE2T) is overexpressed in patient-derived breast cancer samples, and UBE2T overexpression predicts poor prognosi...

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Detalles Bibliográficos
Autores principales: Dutta, Roshan, Guruvaiah, Praveen, Reddi, Kiran Kumar, Bugide, Suresh, Reddy Bandi, Dhana Sekhar, Edwards, Yvonne J K, Singh, Kamaljeet, Gupta, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629447/
https://www.ncbi.nlm.nih.gov/pubmed/36338541
http://dx.doi.org/10.1093/narcan/zcac035