Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules

Cryo-electron microscopy (cryo-EM) is one of the primary methods used to determine the structures of macromolecules and their complexes. With the increased availability of cryo-electron microscopes, the preparation of high-quality samples has become a bottleneck in the cryo-EM structure-determinatio...

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Detalles Bibliográficos
Autores principales: Hrebík, Dominik, Gondová, Mária, Valentová, Lucie, Füzik, Tibor, Přidal, Antonín, Nováček, Jiří, Plevka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629489/
https://www.ncbi.nlm.nih.gov/pubmed/36322417
http://dx.doi.org/10.1107/S2059798322009299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629489/
https://www.ncbi.nlm.nih.gov/pubmed/36322417
http://dx.doi.org/10.1107/S2059798322009299

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