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Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules
Cryo-electron microscopy (cryo-EM) is one of the primary methods used to determine the structures of macromolecules and their complexes. With the increased availability of cryo-electron microscopes, the preparation of high-quality samples has become a bottleneck in the cryo-EM structure-determinatio...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629489/ https://www.ncbi.nlm.nih.gov/pubmed/36322417 http://dx.doi.org/10.1107/S2059798322009299 |