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Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8

Small nuclear ribonucleoprotein complexes (snRNPs) represent the main subunits of the spliceosome. While the assembly of the snRNP core particles has been well characterized, comparably little is known of the incorporation of snRNP-specific proteins and the mechanisms of snRNP recycling. U5 snRNP as...

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Detalles Bibliográficos
Autores principales: Preussner, Marco, Santos, Karine F., Alles, Jonathan, Heroven, Christina, Heyd, Florian, Wahl, Markus C., Weber, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629490/
https://www.ncbi.nlm.nih.gov/pubmed/36322420
http://dx.doi.org/10.1107/S2059798322009755