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Niloticin binds to MD-2 to promote anti-inflammatory pathway activation in macrophage cells

OBJECTIVES: Niloticin is an active compound isolated from Cortex phellodendri with uncharacterized anti-inflammatory activity. We assessed the drug potential of niloticin and examined its ability to target myeloid differentiation protein 2 (MD-2) to ascertain the mechanism for its anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Chen, Guirong, Liu, Chang, Zhang, Mingbo, Wang, Xiaobo, Xu, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629566/
https://www.ncbi.nlm.nih.gov/pubmed/36314579
http://dx.doi.org/10.1177/03946320221133017