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Association between single nucleotide polymorphism SLCO1B1 gene and simvastatin pleiotropic effects measured through flow-mediated dilation endothelial function parameters

BACKGROUND: Atherosclerosis is a condition in which the medium to large arteries become inflamed over time. The cornerstone to the atherosclerosis process is endothelial dysfunction. Simvastatin is a cholesterol-lowering drug known for its endothelial cell pleiotropic properties. The role of genetic...

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Detalles Bibliográficos
Autores principales: Andrianto, Puspitasari, Mia, Ardiana, Meity, Dewi, Ivana Purnama, Shonafi, Khubay Alvia, Kusuma Wardhani, Louisa Fadjri, Nugraha, Ricardo Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629567/
https://www.ncbi.nlm.nih.gov/pubmed/36314075
http://dx.doi.org/10.1177/17539447221132367