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Mettl14-mediated m6A modification enhances the function of Foxp3(+) regulatory T cells and promotes allograft acceptance

N6-methyladenosine (m6A), the most prevalent form of internal mRNA modification, is extensively involved in Treg cells differentiation and function. However, the involvement of m6A in functional Treg cells for transplantation tolerance remains to be elucidated. By using an experimental transplantati...

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Detalles Bibliográficos
Autores principales: Liu, Yanzhuo, Yuan, Yinglin, Zhou, Zili, Cui, Yuanyuan, Teng, Yan, Huang, Hao, Yuan, Hao, Zhang, Yanling, Yang, Lu, Zhao, Gaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629694/
https://www.ncbi.nlm.nih.gov/pubmed/36341394
http://dx.doi.org/10.3389/fimmu.2022.1022015