Cargando…

Mettl14-mediated m6A modification enhances the function of Foxp3(+) regulatory T cells and promotes allograft acceptance

N6-methyladenosine (m6A), the most prevalent form of internal mRNA modification, is extensively involved in Treg cells differentiation and function. However, the involvement of m6A in functional Treg cells for transplantation tolerance remains to be elucidated. By using an experimental transplantati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yanzhuo, Yuan, Yinglin, Zhou, Zili, Cui, Yuanyuan, Teng, Yan, Huang, Hao, Yuan, Hao, Zhang, Yanling, Yang, Lu, Zhao, Gaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629694/ https://www.ncbi.nlm.nih.gov/pubmed/36341394 http://dx.doi.org/10.3389/fimmu.2022.1022015

Ejemplares similares

Corrigendum: Mettl14-mediated m6A modification enhances the function of Foxp3(+) regulatory T cells and promotes allograft acceptance
por: Liu, Yanzhuo, et al.
Publicado: (2022)

Alloantigen-Induced Regulatory T Cells Generated in Presence of Vitamin C Display Enhanced Stability of Foxp3 Expression and Promote Skin Allograft Acceptance
por: Nikolouli, Eirini, et al.
Publicado: (2017)

Shikonin Prolongs Allograft Survival via Induction of CD4(+)FoxP3(+) Regulatory T Cells
por: Zeng, Qiaohuang, et al.
Publicado: (2019)

Roles of the m6A methyltransferases METTL3, METTL14, and WTAP in pulmonary tuberculosis
por: Zhang, Tian-Ping, et al.
Publicado: (2022)

Induced Foxp3(+) T Cells Colonizing Tolerated Allografts Exhibit the Hypomethylation Pattern Typical of Mature Regulatory T Cells
por: Hilbrands, Robert, et al.
Publicado: (2016)

Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4(+) Foxp3(−) T Cells into CD4(+) Foxp3(+) Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival
por: Oyarce, Karina, et al.
Publicado: (2018)

Targeting post-translational modifications of Foxp3: a new paradigm for regulatory T cell-specific therapy
por: Riaz, Farooq, et al.
Publicado: (2023)

FOXP3+ regulatory T cells and the immune escape in solid tumours
por: Qiu, Yiran, et al.
Publicado: (2022)

In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-β-Induced CD4(+)Foxp3(+) Regulatory T Cells
por: Liao, Tao, et al.
Publicado: (2017)

CD4(+)CD25(+)FOXP3(+) regulatory T cells: a potential “armor” to shield “transplanted allografts” in the war against ischemia reperfusion injury
por: Jeyamogan, Shareni, et al.
Publicado: (2023)

UXT is a novel regulatory factor of regulatory T cells associated with Foxp3
por: Li, Weina, et al.
Publicado: (2014)

Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function
por: Teng, Yan, et al.
Publicado: (2021)

The Many Functions of Foxp3(+) Regulatory T Cells in the Intestine
por: Cosovanu, Catalina, et al.
Publicado: (2020)

Inhibition of Allograft Inflammatory Factor-1 in Dendritic Cells Restrains CD4(+) T Cell Effector Responses and Induces CD25(+)Foxp3(+) T Regulatory Subsets
por: Elizondo, Diana M., et al.
Publicado: (2017)

Foxp3 Post-translational Modifications and Treg Suppressive Activity
por: Deng, Guoping, et al.
Publicado: (2019)

A novel prevascularized tissue-engineered chamber as a site for allogeneic and xenogeneic islet transplantation to establish a bioartificial pancreas
por: Liu, Yanzhuo, et al.
Publicado: (2020)

Regulatory T Cells in Pregnancy: It Is Not All About FoxP3
por: Krop, Juliette, et al.
Publicado: (2020)

A New Immunosuppressive Molecule Emodin Induces both CD4(+)FoxP3(+) and CD8(+)CD122(+) Regulatory T Cells and Suppresses Murine Allograft Rejection
por: Qiu, Feifei, et al.
Publicado: (2017)

Analysis of METTL3 and METTL14 in hepatocellular carcinoma
por: Liu, Xiangxiang, et al.
Publicado: (2020)

Corrigendum: A New Immunosuppressive Molecule Emodin Induces both CD4(+)FoxP3(+) and CD8(+)CD122(+) Regulatory T Cells and Suppresses Murine Allograft Rejection
por: Qiu, Feifei, et al.
Publicado: (2020)

Foxp3+ Regulatory T-cells and IL-2: The Moirai of T-cell Fates?
por: Gasteiger, Georg, et al.
Publicado: (2012)

Fast and Efficient Genome Editing of Human FOXP3(+) Regulatory T Cells
por: Van Zeebroeck, Lauren, et al.
Publicado: (2021)

Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon
por: Cantorna, Margherita T., et al.
Publicado: (2019)

The Distinct Function and Localization of METTL3/METTL14 and METTL16 Enzymes in Cardiomyocytes
por: Arcidiacono, Orazio Angelo, et al.
Publicado: (2020)

Peripheral and Thymic Foxp3(+) Regulatory T Cells in Search of Origin, Distinction, and Function
por: Dhamne, Chetan, et al.
Publicado: (2013)

Clinical Outlook for Type-1 and FOXP3(+) T Regulatory Cell-Based Therapy
por: Gregori, Silvia, et al.
Publicado: (2015)

Tissue Resident Foxp3(+) Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
por: Lee, Juyeun, et al.
Publicado: (2022)

Foxp3+ regulatory T cell therapy for tolerance in autoimmunity and solid organ transplantation
por: Sanders, Jes M., et al.
Publicado: (2022)

A Comprehensive Analysis of METTL1 to Immunity and Stemness in Pan-Cancer
por: Gao, Zijie, et al.
Publicado: (2022)

METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications
por: Jian, Dongdong, et al.
Publicado: (2020)

The Role of Regulatory Myeloid Cell Therapy in Renal Allograft Rejection
por: Zhuang, Jingming, et al.
Publicado: (2021)

CD4+FOXP3+ Regulatory T-Cell Subsets in Human Immunodeficiency Virus Infection
por: Simonetta, Federico, et al.
Publicado: (2013)

The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells
por: Brajic, Aleksandra, et al.
Publicado: (2018)

CD4(+)FOXP3(+) Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation
por: Mancusi, Antonella, et al.
Publicado: (2019)

METTL14-dependent m(6)A modification controls iNKT cell development and function
por: Cao, Liang, et al.
Publicado: (2022)

Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
por: Xu, Yeqiu, et al.
Publicado: (2023)

Functional crosstalk between dendritic cells and Foxp3(+) regulatory T cells in the maintenance of immune tolerance
por: Kornete, Mara, et al.
Publicado: (2012)

Antigen-Specificity in the Thymic Development and Peripheral Activity of CD4(+)FOXP3(+) T Regulatory Cells
por: Pohar, Jelka, et al.
Publicado: (2018)

Signaling Through gp130 Compromises Suppressive Function in Human FOXP3(+) Regulatory T Cells
por: Bin Dhuban, Khalid, et al.
Publicado: (2019)

Co-expression of Foxp3 and Helios facilitates the identification of human T regulatory cells in health and disease
por: Morina, Lyra, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kjk6b9f0a0qmuukqjhcenv74ct