Untangling the roles of TOP2A and TOP2B in transcription and cancer

Type II topoisomerases (TOP2) are conserved regulators of chromatin topology that catalyze reversible DNA double-strand breaks (DSBs) and are essential for maintaining genomic integrity in diverse dynamic processes such as transcription, replication, and cell division. While controlled TOP2-mediated...

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Detalles Bibliográficos
Autores principales: Uusküla-Reimand, Liis, Wilson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629710/
https://www.ncbi.nlm.nih.gov/pubmed/36322662
http://dx.doi.org/10.1126/sciadv.add4920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629710/
https://www.ncbi.nlm.nih.gov/pubmed/36322662
http://dx.doi.org/10.1126/sciadv.add4920

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