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Multiplexed high-throughput immune cell imaging reveals molecular health-associated phenotypes

Phenotypic plasticity is essential to the immune system, yet the factors that shape it are not fully understood. Here, we comprehensively analyze immune cell phenotypes including morphology across human cohorts by single-round multiplexed immunofluorescence, automated microscopy, and deep learning....

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Detalles Bibliográficos
Autores principales: Severin, Yannik, Hale, Benjamin D., Mena, Julien, Goslings, David, Frey, Beat M., Snijder, Berend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629716/
https://www.ncbi.nlm.nih.gov/pubmed/36322666
http://dx.doi.org/10.1126/sciadv.abn5631