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Kinetic frustration by limited bond availability controls the LAT protein condensation phase transition on membranes
LAT is a membrane-linked scaffold protein that undergoes a phase transition to form a two-dimensional protein condensate on the membrane during T cell activation. Governed by tyrosine phosphorylation, LAT recruits various proteins that ultimately enable condensation through a percolation network of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629719/ https://www.ncbi.nlm.nih.gov/pubmed/36322659 http://dx.doi.org/10.1126/sciadv.abo5295 |