Notch signaling functions in noncanonical juxtacrine manner in platelets to amplify thrombogenicity

BACKGROUND: Notch signaling dictates cell fate decisions in mammalian cells including megakaryocytes. Existence of functional Notch signaling in enucleate platelets remains elusive. METHODS: Transcripts/peptides of Notch1 and Delta-like ligand (DLL)–4 were detected in platelets isolated from human b...

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Detalles Bibliográficos
Autores principales: Chaurasia, Susheel N, Ekhlak, Mohammad, Kushwaha, Geeta, Singh, Vipin, Mallick, Ram L, Dash, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629830/
https://www.ncbi.nlm.nih.gov/pubmed/36190110
http://dx.doi.org/10.7554/eLife.79590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629830/
https://www.ncbi.nlm.nih.gov/pubmed/36190110
http://dx.doi.org/10.7554/eLife.79590

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