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Notch signaling functions in noncanonical juxtacrine manner in platelets to amplify thrombogenicity

BACKGROUND: Notch signaling dictates cell fate decisions in mammalian cells including megakaryocytes. Existence of functional Notch signaling in enucleate platelets remains elusive. METHODS: Transcripts/peptides of Notch1 and Delta-like ligand (DLL)–4 were detected in platelets isolated from human b...

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Detalles Bibliográficos
Autores principales:	Chaurasia, Susheel N, Ekhlak, Mohammad, Kushwaha, Geeta, Singh, Vipin, Mallick, Ram L, Dash, Debabrata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629830/ https://www.ncbi.nlm.nih.gov/pubmed/36190110 http://dx.doi.org/10.7554/eLife.79590

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