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Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA

Cas7-11 is a Type III-E CRISPR Cas effector that confers programmable RNA cleavage and has potential applications in RNA interference. Cas7-11 encodes a single polypeptide containing four Cas7- and one Cas11-like segments that obscures the distinction between the multi-subunit Class 1 and the single...

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Detalles Bibliográficos
Autores principales: Goswami, Hemant N, Rai, Jay, Das, Anuska, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629832/
https://www.ncbi.nlm.nih.gov/pubmed/36190192
http://dx.doi.org/10.7554/eLife.81678