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Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles

Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-expression in the vestibular end organs. However, AAV has limited usefulness for delivering a large gene, or multiple genes, due to its small packaging capacity (< 5 kb). Co-transduction of dual-AAV vectors ca...

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Detalles Bibliográficos
Autores principales: Chen, Zhong-Rui, Guo, Jing-Ying, He, Lu, Liu, Shan, Xu, Jun-Yi, Yang, Zi-Jing, Su, Wei, Liu, Ke, Gong, Shu-Sheng, Wang, Guo-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629838/
https://www.ncbi.nlm.nih.gov/pubmed/36340687
http://dx.doi.org/10.3389/fnmol.2022.1020803