Cargando…
Development of ASIC1a ligand-gated ion channel drug screening assays across multiple automated patch clamp platforms
Human acid-sensing ion channels (ASIC) are ligand-gated ionotropic receptors expressed widely in peripheral tissues as well as sensory and central neurons and implicated in detection of inflammation, tissue injury, and hypoxia-induced acidosis. This makes ASIC channels promising targets for drug dis...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629855/ https://www.ncbi.nlm.nih.gov/pubmed/36340694 http://dx.doi.org/10.3389/fnmol.2022.982689 |