Antitumor Effect of Low-Dose of Rapamycin in a Transgenic Mouse Model of Liver Cancer

PURPOSE: We investigate whether low-dose rapamycin is effective in preventing hepatocellular carcinoma (HCC) growth and treating HCC after tumor development in transgenic mice. MATERIALS AND METHODS: We established transgenic mice with HCC induced by activated HrasG12V and p53 suppression. Transgeni...

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Detalles Bibliográficos
Autores principales: Lee, Hyung Soon, Kim, Joon Ye, Ro, Simon Weonsang, Kim, Myoung Soo, Kim, Haeryoung, Joo, Dong Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629903/
https://www.ncbi.nlm.nih.gov/pubmed/36303309
http://dx.doi.org/10.3349/ymj.2022.0247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629903/
https://www.ncbi.nlm.nih.gov/pubmed/36303309
http://dx.doi.org/10.3349/ymj.2022.0247

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