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Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior

Depression is one of the most important mental illnesses and is closely related to inflammation. Betaine is a natural product with an anti-inflammatory and antioxidant activities. However, the mechanism by which betaine ameliorates depression-like behaviors induced by lipopolysaccharide (LPS) is poo...

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Detalles Bibliográficos
Autores principales: Zhang, Man, Wang, Xiao-Long, Shi, Hui, Meng, Lan-Qing, Quan, Hong-Feng, Yan, Lin, Yang, Hui-Fang, Peng, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629937/
https://www.ncbi.nlm.nih.gov/pubmed/36339940
http://dx.doi.org/10.1155/2022/9313436