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General Phenotype of NADase Induction by CLI Treatment in Streptococcus pyogenes

The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic-shock syndrome (STSS). However, we previously reported that a “subinhibitory dose” of CLI induced the expression of the NAD-glycohydrolase (NADase) exotoxin in an emm1-type...

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Detalles Bibliográficos
Autores principales: Tatsuno, Ichiro, Isaka, Masanori, Hasegawa, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629962/
https://www.ncbi.nlm.nih.gov/pubmed/36340423
http://dx.doi.org/10.1155/2022/4767765