The Significance of p-AKT1 as a Prognostic Marker and Therapeutic Target in Patients With Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor-2-Positive Early Breast Cancer

PURPOSE: Phosphorylated AKT1 (p-AKT1) at Ser473 is a functional isoform of AKT and a key component of the PI3K/mTOR/AKT pathway. This study aimed to evaluate the prognostic significance of p-AKT1 (Ser473) based on the molecular subtypes of breast cancer. METHODS: To investigate the prognostic value...

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Detalles Bibliográficos
Autores principales: Kim, Ji Yea, Park, Chan Sub, Jang, Se-Kyeong, Seol, Hyesil, Seong, Min-Ki, Noh, Woo Chul, Park, In-Chul, Kim, Hyun-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629968/
https://www.ncbi.nlm.nih.gov/pubmed/36314765
http://dx.doi.org/10.4048/jbc.2022.25.e43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629968/
https://www.ncbi.nlm.nih.gov/pubmed/36314765
http://dx.doi.org/10.4048/jbc.2022.25.e43

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