An Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak β-Cell Mass Acquisition

The increase of functional β-cell mass is paramount to maintaining glucose homeostasis in the setting of systemic insulin resistance and/or augmented metabolic load. Understanding compensatory mechanisms that allow β-cell mass adaptation may allow for the discovery of therapeutically actionable cont...

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Detalles Bibliográficos
Autores principales: Bartolomé, Alberto, Ravussin, Yann, Yu, Junjie, Ferrante, Anthony W., Pajvani, Utpal B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630089/
https://www.ncbi.nlm.nih.gov/pubmed/35944274
http://dx.doi.org/10.2337/db22-0306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630089/
https://www.ncbi.nlm.nih.gov/pubmed/35944274
http://dx.doi.org/10.2337/db22-0306

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