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An Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak β-Cell Mass Acquisition
The increase of functional β-cell mass is paramount to maintaining glucose homeostasis in the setting of systemic insulin resistance and/or augmented metabolic load. Understanding compensatory mechanisms that allow β-cell mass adaptation may allow for the discovery of therapeutically actionable cont...
Autores principales: | Bartolomé, Alberto, Ravussin, Yann, Yu, Junjie, Ferrante, Anthony W., Pajvani, Utpal B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630089/ https://www.ncbi.nlm.nih.gov/pubmed/35944274 http://dx.doi.org/10.2337/db22-0306 |
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