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Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance

The tumor microenvironment (TME) represents a milieu enabling cancer cells to develop malignant properties, while concerted interactions between cancer and stromal cells frequently shape an “activated/reprogramed” niche to accelerate pathological progression. Here we report that a soluble factor epi...

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Detalles Bibliográficos
Autores principales: Wang, Changxu, Long, Qilai, Fu, Qiang, Xu, Qixia, Fu, Da, Li, Yan, Gao, Libin, Guo, Jianming, Zhang, Xiaoling, Lam, Eric W.-F., Campisi, Judith, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630100/
https://www.ncbi.nlm.nih.gov/pubmed/36202915
http://dx.doi.org/10.1038/s41388-022-02476-7