Substrate-driven assembly of a translocon for multipass membrane proteins

Most membrane proteins are synthesized on endoplasmic reticulum (ER)-bound ribosomes docked at the translocon, a heterogeneous ensemble of transmembrane factors operating on the nascent chain(1,2). How the translocon coordinates the actions of these factors to accommodate its different substrates is...

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Detalles Bibliográficos
Autores principales: Sundaram, Arunkumar, Yamsek, Melvin, Zhong, Frank, Hooda, Yogesh, Hegde, Ramanujan S., Keenan, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630114/
https://www.ncbi.nlm.nih.gov/pubmed/36261522
http://dx.doi.org/10.1038/s41586-022-05330-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630114/
https://www.ncbi.nlm.nih.gov/pubmed/36261522
http://dx.doi.org/10.1038/s41586-022-05330-8

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