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The tRNA regulome in neurodevelopmental and neuropsychiatric disease

Transfer (t)RNAs are 70–90 nucleotide small RNAs highly regulated by 43 different types of epitranscriptomic modifications and requiring aminoacylation (‘charging’) for mRNA decoding and protein synthesis. Smaller cleavage products of mature tRNAs, or tRNA fragments, have been linked to a broad vari...

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Detalles Bibliográficos
Autores principales: Blaze, Jennifer, Akbarian, Schahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630165/
https://www.ncbi.nlm.nih.gov/pubmed/35505091
http://dx.doi.org/10.1038/s41380-022-01585-9