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Carvedilol ameliorates dexamethasone-induced myocardial injury in rats independent of its action on the α1-adrenergic receptor

The current study aimed to investigate the cardiotoxic effect of dexamethasone-high-dose in rats, the therapeutic effect of carvedilol and the role of α1-adrenergic receptor (α1AR). The experiment involved 6 groups: control, dexamethasone (10 mg/kg), carvedilol (10 mg/kg), phenylephrine (1 mg/kg), p...

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Detalles Bibliográficos
Autores principales: Mohamed, Rasha M. S. M., Ahmad, Enssaf Ahmad, Omran, Bothina H. F., Sakr, Amr T., Ibrahim, Islam A. A. E.-H., Mahmoud, Mona F., El-Naggar, Mostafa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630193/
https://www.ncbi.nlm.nih.gov/pubmed/36085425
http://dx.doi.org/10.1007/s00210-022-02285-5