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Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring

AIMS/HYPOTHESIS: Metformin is increasingly used to treat gestational diabetes (GDM) and pregnancies complicated by pregestational type 2 diabetes or polycystic ovary syndrome but data regarding long-term offspring outcome are lacking in both human studies and animal models. Using a mouse model, this...

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Detalles Bibliográficos
Autores principales: Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Pantaleão, Lucas C., Pellegrini Pisani, Luciana, Dearden, Laura, Tadross, John A., Aiken, Catherine E., Fernandez-Twinn, Denise S., Ozanne, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630251/
https://www.ncbi.nlm.nih.gov/pubmed/36112170
http://dx.doi.org/10.1007/s00125-022-05789-0