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Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring
AIMS/HYPOTHESIS: Metformin is increasingly used to treat gestational diabetes (GDM) and pregnancies complicated by pregestational type 2 diabetes or polycystic ovary syndrome but data regarding long-term offspring outcome are lacking in both human studies and animal models. Using a mouse model, this...
Autores principales: | Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Pantaleão, Lucas C., Pellegrini Pisani, Luciana, Dearden, Laura, Tadross, John A., Aiken, Catherine E., Fernandez-Twinn, Denise S., Ozanne, Susan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630251/ https://www.ncbi.nlm.nih.gov/pubmed/36112170 http://dx.doi.org/10.1007/s00125-022-05789-0 |
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